State v. Federal Court: What is the difference in criminal defense issues?

Federal court cases are typically investigated by federal agencies, including the FBI, DEA, Customs, Treasury, and other federal agencies. Sometimes state and local agencies also file charges in federal court if the offenses involve major quantity of drugs, weapons or other contraband. The federal government has more resources to prosecute cases, including special units to prosecute drugs, fraud, and violent crimes. While the state and local government also has special units, they have fewer prosecutors with larger case loads. Also, local law enforcement does not have nearly as many resources to complete investigations with as much thoroughness as federal law enforcement. For the most part, it is definitely in a criminal defendant's interest to be prosecuted in state, rather than federal court. The state of California's sentencing system has more flexibility in terms of alternative sentencing options than the United States Sentencing Guidelines.